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1) Mechanistic gaps in cellcell crosstalk and non-classical regulatory pathways: Current research focuses on ferroptosis in individual immune cell types (T cells, neutrophils, B cells, and macrophages) but lacks insights into the intercellular crosstalk that amplifies ferroptosis-driven autoimmunity and renal injury in LN

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Since apoptosis is central to maintaining normal cellular homeostasis, targeting dysregulated apoptotic pathways presents an effective strategy to combat both cancer progression and MDR

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