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Historically marketed as a premium brand, popular among affluent smokers

It can occur even when a person is resting, meaning that the heart consistently does not get enough oxygen

Huxley RR, Woodward M: Cigarette smoking as a risk factor for coronary heart disease in women compared with men: a systematic review and meta-analysis of prospective cohort studies

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For example, a study published in the Journal of Clinical Endocrinology & Metabolism found that smokers had about 15% higher total testosterone and 13% higher free testosterone levels than their non-smoking counterparts