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The 12 mg dose was also associated with reductions in several cardiovascular risk factors , including triglycerides, non-HDL cholesterol, systolic blood pressure and high-sensitivity C-reactive protein

Trade-offs: Fluid retention risk (and other contraindications), slower onset (weeks to months), and careful patient selection

If weight management is your primary goal, you can switch to Wegovy or Zepbound, as both are FDA-approved for weight management

Effects on insulin secretion and sensitivity

Consistently hitting your protein needs is one of the biggest drivers of continued weight loss success on GLP-1 medications