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10.1097/MD.0000000000025076 106 ZhangY.ChenW

This is the first demonstration that oestrone drives greater metastasis of ER + breast cancer models than oestradiol and that oestrone-bound ER activates epithelial-to-mesenchymal transition drivers in breast cancer models

Updated July 2026 Author: Allison Jones, FNP Medically reviewed by Dr

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Studies indicate that GLP-1R (glucagon-like peptide-1 receptor), GIPR (glucose-dependent insulinotropic polypeptide receptor), and GCGR (glucagon receptor) act as crucial "regulators" in maintaining human blood glucose balance and are important therapeutic targets for type 2 diabetes and obesity