dpp 4 inhibitors and glp 1 GLP-1-RA DPP-4 in the management of type 2 diabetes PDF] Effects Of GLP-1 Analogues,

The trial currently has almost 10,000 patients enrolled and is expected to assess a composite MACE endpoint consisting of cardiovascular (CV) death, non-fatal myocardial infarction, or non-fatal stroke in patients with T2D as is expected to readout in July 2024 (NCT03574597)

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Importantly, this success did not arise from the discovery of new biology, but from the translational maturation of a peptide system that had been characterized for decades

DPP-4 inhibitor sitagliptin prevents inflammation and oxidative stress of heart and kidney in two kidney and one clip (2K1C) rats