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This assay utilized recombinant human CSNK1A1 and peptides corresponding to the hinge region of NHR-49 as the substrate to test for direct phosphorylation

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Inhibition of necrosis using necrostatin-1, a potent inhibitor of RIPK1, is associated with reduced dopaminergic cell death in the SN in both in vivo and in vitro models (Wu et al., 2015

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