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Patients on GLP-1 medications notice fewer dips in energy as their bodies adapt to lower calorie intake

Meneghini LF, Hogan AR, Selvaggi G

Genetic predispositions in GLP-1 pathway genes (GLP1R rs6923761, GIPR rs1800437, FTO rs9939609, MC4R rs17782313) may help contextualize expected medication response and guide dose selectionthough genetic testing does not replace clinical assessment or guarantee outcomes

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Furthermore, we analysed clusters of genes differentially expressed in high versus low steatotic livers together with genes found in literature 19,23 and genome-wide association studies 3 (Fig