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Due to the rise in fentanyl-laced pills, treatment for opioid use disorder (OUD), defined as a problematic pattern of opioid use leading to clinically significant impairment or distress [3], has been of high priority [4]

The authors determined significantly higher concentrations of semaglutide in the hypothalamus compared to other parts of the brain, indicating that the drug effectively reaches regions associated with the GLP-1 receptor, which are related to appetite suppression and neuroprotection

2021 May 6;384(18):171930

Also, what are the effects of peptides and where does the evidence lie

Clinical trials have shown that Mounjaro is slightly more effective for weight loss than Wegovy , but the difference is small