Gastrointestinal adverse events were reported by 84.1% with semaglutide and 82.7% with liraglutide
A linear mixed model (LMM) was employed: where is the trait value for individual , is the intercept, is the effect of genetic locus on individual , and are fixed effect covariates, is a random term representing the polygenic effect (using a leave-one-chromosome-out (LOCO) kinship matrix), and is the error term
A licensed provider evaluates the patient, and prescriptions are fulfilled as branded FDA-approved GLP-1 products or compounded semaglutide or tirzepatide via a 503A pathway
If youve recently changed your diet significantly, added or removed exercise, or been under unusual stress, those variables can affect the scale in ways that look like a medication issue but arent
The SURMOUNT-2 trial in patients with type 2 diabetes showed 15.7% weight reduction at 15mg