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There is a difference in terms of the primary outcome, BMI within one group, which favored combination with placebo (MD 1.10, 95% CI [0.321.88]

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According to peer-reviewed literature, unlike synthetic growth hormone replacement (recombinant HGH), secretagogues work with the body's existing feedback mechanisms, which may result in more physiologically natural GH pulsing patterns

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331 Although reductions in systolic and diastolic blood pressure were observed in the treatment groups, these changes did not reach statistical significance, possibly due to the limited sample size and study power