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Severe Gastrointestinal Disease Active gastroparesis Severe inflammatory bowel disease History of pancreatitis (relative contraindication) Relative Contraindications (Use with Caution) 1

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These paralogs lack 4 conserved cysteines that form a pair of CxxC Zn binding motifs (called C ribosomal proteins) present in their Zn binding counterparts (C+,)

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