The compound incorporates three non-standard structural features: an -aminoisobutyric acid (Aib) at the N-terminus bearing no stereocenter, a D-2-naphthylalanine (D-2-Nal) at position 3, and a D-phenylalanine at position 4
Research indicates that a 5%10% reduction in body weight is sufficient to significantly improve insulin sensitivity, reduce androgen levels, and restore ovulatory function in a subset of patients (19, 20, 31)
Options at that point may include switching medications, adding adjunctive therapy, investigating underlying conditions like hypothyroidism or PCOS, or reassessing whether this medication class is right for you
Individuals with certain medical conditions or health concerns, such as kidney disease, liver disease, certain blood disorders, or allergies to specific vitamins, may need to avoid or modify the therapy
Cysteine also exerts a pronounced influence on melanin synthesis within hair follicles, especially pivotal in pheomelanin formation (Lee et al