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The enzymes responsible for these reactions are primarily found in the liver, although they can also be present in other tissues

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Pure DBE (108014, SigmaAldrich) was used as a refractive index matching solution to clear the tissue after dehydration

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That price gap has fueled a parallel market of direct-to-consumer telehealth platforms and, more concerningly, unverified sellers a real risk given how injectable these drugs are and how much counterfeit-drug activity tends to follow any high-demand, high-price medication