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Our studies showed that the effect of liraglutide on body weight was not compromised in vagotomized animals, supporting the concept that GLP-1Rs in the brain, and not gut-to-brain communication, is mostly responsible for the weight loss effect (117)

10.1074/jbc.M808515200 J

10.1021/pr1002609 J Proteome Res

These conditions include gastroparesis (stomach paralysis), cyclic vomiting syndrome, and bowel obstruction

After two to four years of supplementation, they found a significant drop in antibody titers and normalization of thyroid morphology as evidenced by high-resolution USS [42]