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Study identifies benefits, risks linked to popular weight-loss drugs GLP-1 medications tied to decreased risk of dementia, addiction

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Sitagliptin ameliorates busulfan-induced pulmonary and testicular injury in rats through antioxidant, anti-inflammatory, antifibrotic, and antiapoptotic effects

Mechanistically, since SGLT2 is not expressed in cardiomyocytes, SGLT2 inhibitors exert their cardioprotective effects indirectly by targeting noncardiomyocytes, such as by inducing diuresis, modulating neurohormonal activation, and improving metabolism, rather than through direct actions on cardiomyocytes

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