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A multivitamin may be considered for patients with significantly reduced food intake or documented nutritional gaps, though the US Preventive Services Task Force notes insufficient evidence for routine multivitamin use in generally healthy adults

Guralnik, J

No clear association was found between total intake of examined flavonoids and incidence of ovarian cancer (Relative Risk [RR] = 0.75 for the highest versus lowest quintile, 95% confidence interval [CI] = 0.511.09

Preclinical studies in rodent models of cortical contusion and ischemia/reperfusion injury consistently demonstrate that riboflavin administration (typically 120 mg/kg oral or parenteral) reduces lesion volume, brain edema, astrocytosis, and apoptotic cell death, while enhancing sensorimotor recovery and spatial memory performance (8)