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doi: 10.3389/fcvm.2025.1545231 Received 14 December 2024 Accepted 31 March 2025 Published 16 April 2025 Volume 12 - 2025 Edited by Xintian Cai, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, China Reviewed by Qiyao Xu, Nanjing University of Chinese Medicine, China Di Shen, People's Hospital of Xinjiang Uygur Autonomous Region, China Updates Copyright 2025 Liu, Yu, Lu, Liu, Chen and Li

Maternal therapy with ASHMI (4.5 mg/mouse twice daily) was more effective than dexamethasone at decreasing offspring susceptibility to airway disease, characterized by increased IgG2a and decreased BALF C-X-C motif chemokine ligand-1 and eotaxin-1 levels [102]

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In addition, the application of phosphate fertilizers, excess industrial chemical waste, and sewage sludge are actively involved in increasing HMs-toxicity to plants, soils, and environments [3, 4]