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By suppressing NNMT, 5-Amino-1MQ increases NAD levels and helps to accelerate energy metabolism, support healthy body composition, and reduce fat massespecially visceral fat

[PubMed: 12679426] 40

Mutations in the selenocysteine insertion sequence-binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans

One difference between their model and the one reported here is that deletion of Gclc is induced in hepatocytes of adult mice (which are slowly proliferating), compared to theirs, where deletion of Gclc occurred in hepatocytes of growing animals (which are rapidly proliferating)

Benefits: May help reduce fatigue