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This enhancement is demonstrable through an increase in mitochondrial DNA content, the upregulation of genes integral to mitochondrial biogenesis, and the increased expression of proteins pivotal in oxidative phosphorylation

Gross brain regions were obtained from adult Sprague-Dawley rats and acutely frozen in liquid nitrogen

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Ethical principles of the study complied with the European Directive 010/63/E, the Law on Amendments to the Animal Protection Act (Official Gazette 37/13), the Animal Protection Act (Official Gazette 135/06), the Ordinance on the protection of animals used for scientific purposes (Official Gazette 55/13), Federation of European Laboratory Animal Science Associations recommendations and the recommendations of the Ethics Committee of the School of Medicine, University of Zagreb

van Sloten, T