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L-carnitine also supports electron transport chain function and helps remove toxic acyl-CoA metabolites from mitochondria via carnitine acyltransferases
Edgar S, Hopley B, Genovese L, et al
During this process, the mitochondrial matrix reductase ferredoxin 1 (FDX1) functions as a critical upstream regulator by reducing Cu 2 + to the more toxic Cu + species and by promoting LIAS-mediated protein lipoylation
Samples were centrifuged at 3,000 g for 10 min at 4C to create a gradient, followed by removal of the top clear layer and middle debris-containing layer (45 ml)
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