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The glutathione moieties of GSSR and GSH have to interact with different protein areas as a result of the S N 2 geometry of both half-reactions of the ping pong bi-bi mechanism (Fig

Biochem Pharmacol (2013) 85:70517.10.1016/j.bcp.2012.11.016 33 CuadradoAMartin-MoldesZYeJLastres-BeckerI