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NNMT connects nicotinamide metabolism with the cellular methyl-donor system

It has been estimated that the prevalence of pernicious anemia in European countries is approximately 4% of the population ( For patients with pernicious anemia, lifelong vitamin B12 therapy is indicated

Research remains in early stages with no human clinical trials currently approved

Make sure to include these in your meals for adequate levels of vitamin D and B12: High in B12: Beef liver Shellfish (e.g., clams and crab) Salmon and tuna Ground beef Dairy products such as milk, yogurt, and cheese Fortified plant-based milk or cereals High in Vitamin D: Salmon Freshwater trout Sardines Mushrooms exposed to sunlight Fortified milk and cereals When to See a Doctor If you experience persistent symptoms of deficiency or are unsure about your nutrient needs, consult a healthcare provider

I've deliberately gone 12 weeks between injections, just to see if it made any/much difference