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Keywords: exenatide, glp-1 receptor agonists, liraglutide, long-term treatment, obesity management, randomized controlled trials, safety profile, semaglutide, sustained weight loss, tirzepatide Introduction and background Obesity has emerged as a global epidemic, with the World Health Organization estimating that over one billion people worldwide are currently classified as overweight or obese

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doi: 10.1111/dom.14496