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Description

To avoid enzymatic cleavage by DPP-4, the N-terminal penultimate amino acid has been replaced with other amino acids (albiglutide, dulaglutide, and semaglutide) or added with a fatty acid moiety (liraglutide and semaglutide), so that albumin binds and shields the enzymatic attack site

(2021) 7:e07615

As a high-stability pentadecapeptide, it is widely studied in laboratory and preclinical models for its influence on key biological processes involved in tissue repair and regeneration