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33 Impaired activity of the folate-dependent enzyme complex in this system results in uracil being misincorporated into DNA in the place of thymine, with subsequent DNA instability

doi: 10.1016/j.theriogenology.2011.11.006 83 PartykaA.NiaskiW

Hayes BD, Klein-Schwartz W, Doyon S

Notably, ITT assessment revealed that, after insulin administration, untreated GDM rats were unable to significantly reduce the blood glucose, indicating that GDM rats suffered from a peripheral response deficiency to insulin and thus were unable to utilize exogenously injected insulin to drop the increased levels of blood glucose

Additionally, low levels of glutathione in the body will increase ageing, so its a key component in slowing the ageing process