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Additional ultrastructural changes may rarely include dilated granular endoplasmic reticulum, paracrystalline mitochondrial inclusions, and dilation of bile canaliculi, which is a result of impaired excretion of conjugated bilirubin and other organic anions from hepatocytes into the bile canaliculi

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These cells survive harsh conditions and naturally travel to damaged tissue to support repair of cartilage, bone, nerve, and other cell types