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During a drug holiday specifically, sleep quality becomes even more important because you have lost the medication-driven appetite suppression that previously compensated for suboptimal sleep habits

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[8] [9] These medications also act on receptors in the central nervous system, particularly in areas regulating appetite and food reward pathways

J Neuroinflammation 16(1):217 Jiang L, Zhang Y, Jing F, Long T, Qin G, Zhang D, Chen L, Zhou J (2021) P2 7R-mediated autophagic impairment contributes to central sensitization in a chronic migraine model with recurrent nitroglycerin stimulation in mice

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