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Recently, the STEP-HFpEF trial sought to examine the results of 2.4 mg weekly treatment with semaglutide for 52 weeks on various outcomes related to HFpEF and obesity

"In your notification to the Agency, provide a summary of your remediations to demonstrate that you have appropriately completed all CAPA," the agency added

The company is also eligible for $77.5 million in milestones plus sales-based royalties for each additional program

This consistent pattern across multiple trials suggests the dual agonist approach offers genuine advantages over single GLP-1 agonism

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