tirzepatide trial cardiovascular outcomes results july 2025 Reduction of prevalence of patients meeting the criteria for Tirzepatide demonstrates cardiovascular protection in

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Based on clinical trials Mechanism How it works Tirzepatide is often referred to as a "Twincretin" because of its dual-action mechanism which provides more comprehensive metabolic support than GLP-1-only medications: GIP Receptor Activation: Enhances insulin secretion and helps regulate fat metabolism, which may contribute to better weight loss results and fewer gastrointestinal side effects for some patients

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The most common gastrointestinal side effects in the 0.4 mg group included nausea, constipation, decreased appetite, vomiting, and abdominal pain, occurring more frequently than in the placebo group

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