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In response to supply shortages of Wegovy , Excellus BCBS has enhanced criteria for weight management policies

Seek urgent medical attention if light-headedness is accompanied by: Severe or persistent hypoglycaemia symptoms including confusion, sweating, tremor, palpitations, or difficulty concentrating Chest pain or palpitations which may indicate cardiovascular complications Severe dehydration signs include reduced urine output, dark urine, extreme thirst, or dry mucous membranes Fainting or loss of consciousness even brief episodes warrant investigation Visual disturbances blurred vision, double vision, or visual field defects Severe headache particularly if sudden onset or unlike previous headaches Difficulty breathing or speaking which may suggest a serious adverse reaction Call 999 immediately for severe chest pain, severe breathlessness, loss of consciousness, or symptoms of stroke

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Investigating local administration through phase 1 safety and pharmacokinetic trials is a critical first step to bypass the BRB and maximize retinal tissue exposure while minimizing systemic side effects

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