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Int J Genomics (2018) 2018:113

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UV rays are the primary driver of melanin production

Additionally, iron can increase ALOX or EGLN proline hydroxylase (also known as PHD) activity, affecting cellular lipid peroxidation and oxygen homeostasis and thereby influencing cellular ferroptotic processes [40]

Statements Data availability statement All datasets generated for this study are included in the article/Supplementary Material