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Additionally, the 7nAChRs regulate GABAergic projections and synchronize neuronal activity, which is essential for cognitive functions like working memory [43]

When sleep is insufficient or mistimed, these regulatory mechanisms dysfunction, leading to elevated DPP-4 activity particularly during typical eating hours

Kim, B., Kim, H

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Some research indicates that weight reduction can lead to normalisation of cortisol patterns , though findings are inconsistent and depend on individual factors such as the degree of weight loss, baseline metabolic health, and psychological stress levels