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La GLP-1 endgena tiene una vida media de aproximadamente 2-3 minutos porque es rpidamente degradada por la enzima dipeptidil peptidasa-4 (DPP-4)
They demonstrated that human pancreatic tumor and stellate cells activate/process GSAO into its active metabolite and that GT activity positively correlates with GSAO-mediated proliferation arrest of co-cultured endothelial cells ( Figure 3B )
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Sustained Gs signaling mediated by vasopressin type 2 receptors is ligand dependent but endocytosis and -arrestin independent
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