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Their findings suggest that disrupting the barrier could provide a new therapeutic technique for halting tumor growth and preventing metastasis [74]

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Metformin has separately shown wound healing benefits: a 2021 randomized trial (N=108) of topical metformin on diabetic foot ulcers found a 52% complete healing rate at 12 weeks versus 31% with standard care alone (P=0.02) [11]

PMID 10368185

Its possible to bleed, bruise, or scar from injections