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The induction of GADD45A expression and G1 arrest by fucoxanthin was positively regulated by inhibiting p38 MAPK pathway in HepG2 cells and negatively regulated by inhibiting SAPK/JNK pathway in DU145 cells [29]

While the data doesnt establish a direct causeand-effect relationship, it strongly suggests that regular mushroom consumption is correlated with a reduced incidence of dementia, even when adjusted for potential confounding factors

GE2 treatment resulted in loss of visceral fat (GWAT), however, this was dependent on diet and sex

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