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2012 Dec;50(10):1169-73

Mechanistically, GLP-1RAs suppress innate immune responses by downregulating pro-inflammatory cytokines such as IL-1 and IL-6, while upregulating adiponectin, an anti-inflammatory adipokine [361, 381, 382]

The glucose-dependent mechanism of insulin release distinguishes GLP-1 agonists from many other antidiabetic medications, resulting in a lower risk of hypoglycemia when used as monotherapy

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