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Tirzepatide is available in weekly subcutaneous doses of 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg (Table 1).50,51 The initial dosing regimen of tirzepatide is 2.5 mg weekly, with the dose increased to up to 15 mg weekly usually after one month at the previous dose.50,51 Pharmacokinetics of GLP-1 RAs and a Dual GLP-1/GIP RA Numerous studies have reported the pharmacokinetics of these drugs, with each study showing varying pharmacokinetic parameters based on differences in the clinical study design, pharmacokinetic parameter calculation approaches, or analytical methods

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