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Interestingly, NFS1 loss promoted a discernable retention of matrix GSH under 12 h of cystine starvation but did not further enhance the significant effect that CHAC1 had on mitochondrial GSH (Fig

These systems include enzymatic antioxidants such as superoxide dismutase (SOD), catalase, and glutathione peroxidase, as well as non-enzymatic antioxidants like vitamins C and E, glutathione, and albumin ( When this balance is disrupted, however, oxidative stress occurs, leading to significant sperm dysfunction

These effects were observed in APPswe/PSEN1dE9 mice with a C57BL/6 background treated with 100 mg/kg for 30 days, demonstrating its potential role in vascular health and AD symptom management (Kaushik et al., 2018)

Stabilization of the nitric oxide (NO) system, important for vascular function and repair processes