However, the first brain region that was selected for DBS in epilepsy patients was the cerebellum, in effort to counter the hyperexcitability of thalamo-cortical pathways [102]
JAHA 2020 (esmolol crossover RCT confirming -blockade independence and unchanged HRV, so sympathetic activation is not the mediator)
Recently, this molecule has drawn much attention because of its interaction with other signaling molecules and phytohormones
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