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FDA's 2024 review states the mechanism of action is still unknown, which limits how confidently any specific physiological effect can be predicted in humans

The maintenance dose is generally 1500mcg once a month, or at a schedule determined by the physician based on the patient's ongoing clinical needs and blood test results

Drug Reactions BPC-157 has been shown to reduce the adverse effects of NSAIDs, psychiatric drugs, and several cardiac treatments

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That distinct mechanism is exactly why it is discussed as a complement to GLP-1 or GIP/GLP-1 agonists rather than a substitute