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Although most trials have shown some AEs, only a few patients have reported discontinuation of LC because of serious AEs, including one patient with multiple sclerosis who discontinued the trial because of the development of insomnia and nervousness on LC [68]
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When used appropriately, they can improve key aspects of sperm quality, including motility and DNA stability, and may increase the success rates of reproductive treatments using frozen-thawed sperm [33, 35]
Intrathecal administration of exenatide upregulated IL-10 and -endorphin expression in spinal microglia of neuropathic rats [63]
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