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Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

It also cleans up any heavy metals and regulates the body's nitric-oxide cycle, which is vital to homeostasis

2021;10(2):e2001096

In murine models of cachexia, ketogenic feeding preserved lean mass and extended survival, an outcome attributed to reduced systemic IL-6 and TNF- as well as direct effects of ketone bodies (primarily -hydroxybutyrate) on muscle proteolysis 376,377,378