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Proteins of the polycomb group are transcriptional repressors that modify chromatin and promote cancer processing by epigenetic modifications

While these data formed the basis of early enthusiasm, later peptide clinical trials showed that such results did not translate meaningfully into clinical efficacy

10.1167/iovs.63.4.27 69 WangL.ZhangL.NiuY.SitiaR.WangC

The Williams Lab has long been interested in neurons in the hypothalamus that play an important role in mediating hunger, which in turn affects body weight